Thyroid Ablation: What to Expect Before, During, and After

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Thyroid ablation is a medical procedure used to treat thyroid conditions such as hyperthyroidism and thyroid cancer. Understanding what to anticipate before, during, and after thyroid ablation is crucial for a positive and successful experience, regardless of whether you’re considering it as a treatment option or have an appointment for it. From preparation and recovery to potential risks and benefits, this comprehensive guide will provide you with the information you need to navigate thyroid ablation with confidence and peace of mind.

Preparing for Thyroid Ablation

To guarantee a safe and effective thyroid ablation procedure, there are a number of prerequisites that must be completed before the procedure. In addition to assessing your general health, your healthcare practitioner is likely to perform blood tests and imaging examinations to determine the size and function of your thyroid gland. You may need to stop taking specific drugs in the days before the treatment, such as antithyroid or thyroid hormone replacement therapy, depending on the kind of thyroid ablation you’re having. 

Understanding the Procedure

Either ethanol ablation or radioactive iodine treatment (RAI) is often used for thyroid ablation. In radioactive iodine administration (RAI), thyroid cells absorb the radioactive iodine and are subsequently destroyed inside. Thyroid cancer and hyperthyroidism are two major conditions treated with this treatment. At the same time, ethanol ablation is injecting ethanol, or alcohol, directly into thyroid nodules or cysts in order to either shrink or eliminate them. This procedure is often used to treat benign thyroid nodules that are causing symptoms or cosmetic concerns. Both ethanol ablation and RAI are minimally invasive procedures that are carried out under local anesthetic on an outpatient basis. 

What to Expect During Thyroid Ablation

Arriving at the medical facility on the day of your thyroid ablation operation will be your first step toward the procedure. It’s possible that you’ll be asked to change into a hospital gown and given an IV line so that medications and fluids may be given to you. You may need to take specific medicines or have other imaging examinations done before the treatment, depending on the kind of thyroid ablation you’re having. When you’re ready, your doctor will carry out the thyroid ablation treatment, which normally takes between thirty and sixty minutes to finish. You could feel discomfort or pressure throughout the process when the ethanol or radioactive iodine is being given, but this should be mild and tolerable. 

Recovering from Thyroid Ablation

You will have thorough monitoring after thyroid ablation to make sure no problems arise right away. Depending on the type of thyroid ablation you had, you could be required to stay in the hospital for observation, or you might be allowed to go home soon after. After thyroid ablation, you can have a few mild side effects, such as nausea, sore throat, or neck pain, but these usually go away in a few days. Your healthcare professional can prescribe medication to assist in treating symptoms or ease discomfort. 

Risks and Considerations

Before beginning therapy, you should discuss the risks and concerns associated with thyroid ablation with your healthcare practitioner, as with any medical operation. Thyroid ablation has several potential risks, such as transient or permanent alterations in thyroid function, damage to neighboring organs or tissues, and allergic responses to drugs or contrast agents. Furthermore, there can be certain risks associated with radioactive iodine treatment, such as radiation exposure and the chance of thyroid cancer returning. It’s important to talk about these concerns with your healthcare physician and consider how beneficial thyroid ablation could be for your particular situation.

Follow-Up Care and Monitoring

You will need regular follow-up checkups and monitoring after thyroid ablation in order to evaluate thyroid function and guarantee the procedure’s effectiveness. Blood tests and imaging examinations can be used by your healthcare practitioner to assess the size and function of your thyroid gland and to keep an eye out for any issues or recurrences. To best support your thyroid health, your physician can prescribe different medications or other therapies based on the results of these tests. To maintain your continued health and well-being, you must show up for all planned follow-up sessions and let your healthcare provider know about any changes or concerns you may have.


In conclusion, undergoing thyroid ablation can be a significant step in managing thyroid conditions such as hyperthyroidism and thyroid cancer. With confidence and peace of mind, you can approach thyroid ablation by knowing what to anticipate before, during, and after the treatment. Thyroid ablation is a viable therapeutic option for enhancing thyroid function and general health if it is implemented with appropriate planning, supervision, and aftercare. Remember to communicate openly with your healthcare team, adhere to all pre and post-operative instructions, and attend regular follow-up appointments to ensure the best possible outcomes.

Article edited and fact checked by our editorial team.

Author bio:

Miranda Spears

Miranda Spears is a Texas native who after graduating from University of Texas at Austin, spends her time as a freelance writer.

When not writing, Miranda enjoys horseback riding, shopping, trying new recipes, and spending time with her lovely little pug, Gizmo.


  • Becky McCann, MSN BSN RN ENC, David Hughes, MD. Edited by: Brittany Batell, MPH MSW. Thyroid Nodule Ablation: PostProcedure Patient Instructions. University of Michigan Health.
  • Muhammad H, Santhanam P, Russell JO. Radiofrequency ablation and thyroid nodules: updated systematic review. Endocrine. 2021 Jun;72(3):619-632. doi: 10.1007/s12020-020-02598-6.
  • Kandil E, Omar M, Aboueisha M, Attia AS, Ali KM, Abu Alhuda RF, Issa PP, Wolfe S, Omari S, Buti Y, Abozaid O, Toraih E, Shama MA, Lee G, Tufano RP, Russell JO. Efficacy and Safety of Radiofrequency Ablation of Thyroid Nodules: A Multi-institutional Prospective Cohort Study. Ann Surg. 2022 Oct 1;276(4):589-596. doi: 10.1097/SLA.0000000000005594.